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Introduction

The idea behind this website was to create a central place that combines information, tips and code (templates) for anything related to population PKPD modeling, focussing on NONMEM. A lot of information is available however, it is scattered over the internet. A lot of time is spend finding the right information. Also, little information is available for people starting out with NONMEM analysis. Additionally, useful code templates and code snippets will be placed on the website, which can be directly copied and pasted into the users analysis.

NONMEM
NONMEM (Nonlinear Mixed Effects Modeling) is software used for fitting pharmacokinetic models. (NONMEM). Information concerning NONMEM, creating a NONMEM database and creating model files can be found under the tab NONMEM.

R
R is a free program for statistical analysis computing and graphics. R is very useful when working with (large) databases. NONMEN with Pirana and PsN can be directly used with R to visualize the data and models. (R-project website). Actions can be automated by writing R scripts to speed up the repetitive processes in PK analysis. NONMEM, R and PsN can be directly initialized via Pirana. Information and codes for using R in PK analysis can be found under the tab 'R'.

This website is a work in progess and will be regularly updated.

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